Based on the current situation of nuclear power projects under construction, this paper analyzes the weak links and difficulties of current quality management, puts forward the control content which focus on managers and human activities, and formulates detailed work flow from aspects of training personnel"s quality awareness and responsibility, improve operation skills and skill level. According to the quality plan and construction scheme, operate according to the procedures, especially for the weak links in the quality management, The paper puts forward the PDCA cycle method of root cause analysis and quality management, takes uncivilized construction and environmental remediation as potential safety hazards to improve the management level of targeted solutions and suggestions; the effective implementation of measures and opinions can promote nuclear power projects under construction Objective to construct smoothly and improve the quality management level of nuclear power projects.